exe_registrar@nfsu.ac.in (079) 239 77103
deep.pooja@nfsu.ac.in
079 239 77138
9 Years

Dr. Deep Pooja

Designation : Assistant professor Qualification : Ph. D. Experience : 9 Years

Specialization

Pharmaceutical Sciences

Research Area

Targeted Drug and gene delivery, Nanobiomaterials, and Nanomedicines

Patent(s)

One Indian patent filed.

Book(s) Chapter(s)

  • AK Jangid, P Jain, D Pooja, H Kulhari. (2021) Introduction to Nanomedicines: Basic Concept and Applications. In Emerging Trends in Nanomedicine. Ed.: Sanjay Singh. Springer. (Just Accepted)
  • DB Rai, D Pooja, H Kulhari. (2021)Functionalization of the Dendrimers. In Dendrimers Nanomedicine. Eds: N Misra and K Jain.CRC Press. (Just Accepted) 
  • L Tunki, SK Bhargava, D Pooja. (2020) Pharmacokinetic considerations in design of dendrimer-based nanomedicines. In Pharmaceutical Applications of Dendrimers, AS Chauhan and H Kulhari, Elsevier, 93-106. 
  • DB Rai, D Pooja, H Kulhari. (2020) Dendrimers in gene delivery. In Pharmaceutical Applications of Dendrimers, AS Chauhan and H Kulhari, Elsevier, 211-231. 
  • DB Rai, N Gupta, D Pooja, H Kulhari. (2020) Dendrimers for diagnostic applications. In Pharmaceutical Applications of Dendrimers, AS Chauhan and H Kulhari, Elsevier, 291-324.  
  • L Tunki, R Sistla, D Pooja. (2020) Dendrimer-based targeted drug delivery. In Pharmaceutical Applications of Dendrimers, AS Chauhan and H Kulhari, Elsevier,107-129 
  • D Pooja, R Sistla.(2019) Design of Eco-Friendly Gold Nanoparticles for Cancer Treatment. In: RNA Interference and Cancer Therapy. Lekha Dinesh Kumar, Springer, 215-221. 
  • N Gupta, DB Rai, AK Jangid, D Pooja, H Kulhari. (2019) Efficient systemic delivery of siRNA using different nanocarriers. In Recent Trends and Future Perspectives of Nanotechnology in Modern Animal Biotechnology. Sanjay Singh and Pawan Maurya. Springer, 67-114. 
  • D Pooja, R Sistla, H Kulhari. (2018) Dendrimer-drug conjugates: synthesis strategies, stability and application in anticancer drug delivery. In Design of Nanostructures for Thernostic Applications. Alexandru Mihai Grumezescu, Elsevier, 227-304. 
  • D Pooja, A Kadari, R Sistla. (2018) Lipid-based nanomedicines: Current clinical status and Future perspectives. In Lipid Nanocarriers for Drug Targeting. Alexandru Mihai Grumezescu, Elsevier, 509-528. 
  • H Kulhari, D Pooja, S Shrivastava, TS Reddy, AK Barui, CR Patra, VGM Naidu, DJ Adams, R Sistla. (2016) Cyclic-RGDfK-Directed Docetaxel Loaded Nanomicelles for Angiogenic Tumor Targeting. In Methods in Pharmacology and Toxicology. Humana Press, a part of Springer Science and Business Media.1-12.

Publication(s)

  1. Ashok Kumar Jangid, Raghu Solanki, Sunita Patel, Deep Pooja*, Hitesh Kulhari (2022). Genistein encapsulated inulin-stearic acid bioconjugate nanoparticles: Formulation development, characterization and anticancer activity. International Journal of Biological Macromolecules, 206, 213-21. (IF: 6.953).
  2. Khushboo Kourani, Poonam Jain, Aviral Kumar, Ashok Kumar Jangid, Guruprasadh Swaminathan, Varsha Reddy Durgempudi, Jedy Jose, Rithvik Reddy, Deep Pooja, Hitesh Kulhari, Lekha Dinesh Kumar (2022). Inulin coated Mn3O4 nanocuboids coupled with RNA interference reverse intestinal tumorigenesis in Apc knockout murine colon cancer models. Nanomedicine: Nanotechnology, Biology and Medicine, 40, 102504 (IF: 6.458).
  3. Jain, K Patel, AK Jangid, A Guleria, S Patel, D Pooja*, H Kulhari. (2021) Biotinylated Mn3O4 nanocuboids for targeted delivery of gemcitabine hydrochloride to breast cancer and MRI applications. International Journal of Pharmaceutics 606, 120895. (IF: 5.875).
  4. AK Jangid, K Patel, P Jain, S Patel, K Medicherla, D Pooja*, H Kulhari. (2021) Carrier-free resveratrol nanoparticles: Formulation development, In-vitro anticancer activity, and oral bioavailability evaluation. Materials Letters 302, 130340. (IF: 3.423).
  5. AK Jangid, D Pooja¥, P Jain, N Gupta, S Ramesan, H Kulhari. (2021) Selfassembled and pH-responsive polymeric nanomicelles impart effective delivery of paclitaxel to cancer cells. RSC Advances 11 (23), 13928-13939. (IF: 3.361). ( ¥ Equal contribution)
  6. D Pooja, TS Reddy, Kadari, DJ Adams, V Bansal, R Sistla. (2020) N-acetyl-d-glucosamine-conjugated PAMAM dendrimers as dual receptor-targeting nanocarriers for anticancer drug delivery. European Journal of Pharmaceutics and Biopharmaceutics, 154: 377-386. (IF: 5.571).
  7. P Jain, K Patel, AK Jangid, A Guleria, S Patel, D Pooja*, H Kulhari. (2020) Modulating the delivery of 5-Fluorouracil to human colon cancer cells using multifunctional arginine coated manganese oxide nanocuboids with MRI properties. ACS Applied Bio Materials. (IF: NA, New Journal)
  8. AK Jangid, K Patel, P Jain, S Patel, N Gupta, D Pooja*, H Kulhari. (2020) Inulin-pluronic-stearic acid based double folded nanomicelles for pH-responsive delivery of resveratrol. Carbohydrate Polymers, 116730. (IF: 9.381).
  9. P Jain, S Bhagat, L Tunki, AK Jangid, S Singh, D Pooja*, H Kulhari. (2020) Serotonin-Stearic Acid Bioconjugate Coated Completely Biodegradable Mn3O4 Nanocuboids for Hepatocellular Carcinoma Targeting. ACS Applied Materials & Interfaces. 12, 9, 10170-10182. (IF=9.229)
  10. JR Kumar, ER Reddy, N Mirzadeh, TS Reddy, AK Vardhaman, L Giribabu, B Sridhar, D Pooja, R Sistla, S Bhargava, RTrivedi. (2020) (η6-Arene) ruthenium (II) complexes with ferrocene-tethered salicylaldimine ligands: synthesis, characterization and anti-cancer properties. Polyhedron, 114829. (IF: 3.052).
  11. AK Jangid, P Jain, K Medicherla, D Pooja*, H Kulhari. (2020) Solid-State Properties, Solubility, Stability and Dissolution Behaviour of Co-Amorphous solid dispersions of Baicalin. CrystEngComm. (IF: 3. 545).
  12. L Tunki, AK Jangid, D Pooja, SK Bhargava, R Sistla, H Kulhari. (2020) Serotonin-Functionalized Vit-E Nanomicelles for Targeting of Irinotecan to Prostate Cancer Cells. ACS Applied Bio Materials 3 (8), 5093-5102 (IF: NA, New Journal).
  13. AK Jangid, H Agraval, N Gupta, P Jain, UCS Yadav, D Pooja*, H Kulhari. (2020) Amorphous nanomorin outperforms native molecule in anticancer activity and oral bioavailability. Drug Development and Industrial Pharmacy. 46 (7): 1123-1132. (IF: 3.325).
  14. S Karamchedu, L Tunki, D Pooja*. (2020) Morin Hydrate Loaded Solid lipid nanoparticles: Characterization, Stability, Anticancer activity, and Bioavailability. Chemistry and Physics of Lipids 233, 104988. (IF: 3.329).
  15. AK Jangid, H Agraval, DB Rai, P Jain, UCS Yadav, D Pooja*, H Kulhari. (2020) Baicalin Encapsulating Lipid-Surfactant Conjugate Based Nanomicelles: Preparation, Characterization and Anticancer Activity. Chemistry and Physics of Lipids,233: 104978. (IF: 3.329).
  16. AK Jangid, D Pooja, P Jain, SVK Rompicharla, S Ramesan, H Kulhari*. (2020) Nanoscale, biocompatible and amphiphilic prodrug of cabazitaxel with improved anticancer efficacy against 3D spheroids of prostate cancer cells. Materials Advances. (Just accepted). (IF: NA, New Journal)
  17. N Gupta, S Bhagat, M Singh, AK Jangid, V Bansal, S Singh, D Pooja*, H Kulhari. (2020) Site-specific delivery of a natural chemotherapeutic agent to human lung cancer cells using biotinylated 2D rGOnanocarriers. Material Science and Engineering C. 112, 110884.(IF: 7.328)
  18. TS Reddy, D Pooja¥, SH Priver, RB Luwor, N Mirzadeh, S Ramesan R Sistla, S Karri, M Kuncha, SK Bhargava. (2019) Potent and selective cytotoxic and anti-inflammatory gold(III) compounds containing cyclometallated phosphine sulfide ligands.    Chemistry - A European Journal.  Just accepted, (IF=5.236)(¥ Equal contribution)
  19. P Weerathunge, D Pooja¥, M Singh, EL.H Mayes, V Bansal, R Ramanathan. (2019)Transferrin-conjugated quasi-cubic SPIONs for cellular receptor profiling and detection of brain cancer.   Sensors and Actuators B: Chemical 297, 126737. (IF=7.460)(¥ Equal contribution)
  20. D Pooja, A Gunukula, N Gupta, DJ Adams, H Kulhari. (2019) Bombesin receptor as potential targets for anticancer drug delivery and imaging. The International Journal of Biochemistry & Cell Biology 114,105567. (IF=5.085)
  21. L Tunki, L Nayak, M Kuncha, S Bhargava, D Pooja*, R Sistla. (2019) Modulating the site-specific oral delivery of sorafenib using sugar-grafted nanoparticles for hepatocellular carcinoma treatment          European Journal of Pharmaceutical Sciences 137: 104978 (IF=4.384)
  22. R Radhakrishnan, D Pooja*, H Kulhari, S Gudem, HG Ravuri, S Bhargava, R Sistla. (2019)   Bombesin conjugated solid lipid nanoparticles for improved delivery of epigallocatechin gallate for breast cancer treatment. Chemistry and Physics of Lipids 224, 104770 (IF=3.329).
  23. N Gupta, AK Jangid, D Pooja*, H Kulhari. (2019)Inulin: A novel and stretchy polysaccharide tool for biomedical and nutritional applications. International Journal of Biological Macromolecules 132, 852-863. (IF=6.953)
  24. AK Jangid, H Agraval, N Gupta, UCS Yadav, R Sistla, D Pooja, H Kulhari. (2019). Designing of fatty acid-surfactant conjugate based nanomicelles of morin hydrate for simultaneously enhancing anticancer activity and oral bioavailability. Colloids and Surfaces B: Biointerfaces175, 202-211.(IF=5.268)
  25. A Kadari, D Pooja, RH Gora, S Gudem, VRM Kolapalli, H Kulhari, R Sistla. (2018) Design of multifunctional peptide collaborated and docetaxel loaded lipid nanoparticles for antiglioma therapy. European Journal of Pharmaceutics and Biopharmaceutics 132:168-179. (IF=5.571)
  26. N Gupta, AK Jangid, M Singh, D Pooja*, H Kulhari. (2018) Designing two? dimensional nanosheets for improving Drug Delivery to fucose?receptor? overexpressing cancer cells. ChemMedChem 13(24):2644-2652. (IF=3.466)
  27. AK Jangid, D Pooja, H Kulhari. (2018) Determination of solubility, stability and degradation kinetics of morin hydrate in physiological solutions. RSC Advances8 (50), 28836-28842(IF=3.361)
  28. MK Singh, D Pooja, Halley Gora, AnushaGunukula, R Sistla. (2018) Fabrication of surfactant-stabilized nanosuspension of naringenin to surpass its poor physiochemical properties and low oral bioavailability. Phytomedicines 40:48-54.(IF=5.340)
  29. H Kulhari, TS Reddy, D Pooja, R Shukla, R Sistla, V Bansal, DJ Adams Peptide grafted and self-assembled poly(glutamic acid)-phenylalanine nanoparticles for targeting camptothecin to glioma. Nanomedicine UK 12(14):1661-1674. (IF: 5.307).
  30. MK Singh, D Pooja, SK Jain, R Sistla, AS Chauhan (2017). Poly (amidoamine) dendrimer-mediated hybrid formulation for combination therapy of ramipril and hydrochlorothiazide. European Journal of Pharmaceutical Sciences96: 84-94. (IF=4.384).
  31. D Pooja, H Kulhari, M Kuncha, SS Rachamalla, D Adams, V Bansal, R Sistla (2016). Lectin conjugated solid lipid nanoparticles for targeted delivery of paclitaxel to lung cancer. Molecular Pharmaceutics. 13(11):3903-3912.(IF=4.939).
  32. D Pooja, H Kulhari, DJ Adams, R Sistla (2016). Formulation and dosage of therapeutic nanosuspension for active targeting of docetaxel (WO 2014210485A1). Expert Opinion on Therapeutic Patents 26(7):745-749. (IF=6.674).
  33. H Kulhari, D Pooja, S Shrivastava, M Kuncha, VGM Naidu, DJ Adams, R Sistla (2016). Trastuzumab-grafted PAMAM dendrimers for the selective delivery of anticancer drugs to HER2-positive breast cancer. Scientific Reports (Nature Publishing Group) 6:23179. (IF=4.379).
  34. R Radhakrishnan, D Pooja, S Gudem, S Bhargava, R Shukla, R Sistla (2016). Encapsulation of biophenolic anticancer phytochemical Epigallocatechin gallate within lipid nanoparticles for enhancing its stability and cytotoxicity against cancer. Chemistry and Physics of Lipids198:51-60. (IF=3.329).
  35. H Kulhari, D Pooja, Raju Kota, SR Telukutala, DJ Adams, R Sistla (2016). Cyclic RGDfK peptide functionalized polymeric nanocarriers for targeting gemcitabine to ovarian cancer cells. Molecular Pharmaceutics 13(5):1491-500. (IF: 4.939).
  36. D Pooja, L Tunki, H Kulhari, BB Reddy, R Sistla (2015). Optimization of solid lipid nanoparticles prepared by a single emulsification-solvent evaporation method. Data in Brief 6, 15-19.
  37. H Kulhari, D Pooja, S Shrivastava, SR Telukutala, AK Barui, CR Patra, R Sistla, DJ Adams (2015). Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenictumours. Nanomedicine: Nanotechnology, Biology and Medicine 11 (6), 1511-1520 (IF=6.458).
  38. D Pooja, H Kulhari, L Tunki, S Chinde, M Kuncha, P Grover, SS Rachamalla, R Sistla (2015). Nanomedicines for targeted delivery of etoposide to non-small cell lung cancer using transferrin functionalized nanoparticles. RSC Advances 5 (61), 49122-49131. (IF=3.361)
  39. D Pooja, S Panyaram, H Kulhari, B Reddy, SS Rachamalla, R Sistla (2015). Natural polysaccharide functionalized gold nanoparticles as biocompatible drug delivery carrier.  International Journal of Biological Macromolecules 80, 48-56. (IF=6.953)
  40. D Pooja, L Tunki, H Kulhari, BB Reddy, R Sistla (2015). Characterization, biorecognitive activity and stability of WGA grafted lipid nanostructures for the controlled delivery of rifampicin. Chemistry and Physics of Lipids193, 11-17. (IF=3.329).
  41. H Kulhari, D Pooja, MK Singh, M Kuncha, DJ Adams, R Sistla (2015).Bombesin-conjugated nanoparticles improve the cytotoxic efficacy of docetaxel against gastrin-releasing but androgen-independent prostate cancer. Nanomedicine UK 10 (18), 2847-2859. (IF=5.307)
  42. H Kulhari, D Pooja, SVK Rompicharla, R Sistla, DJ Adams. (2014)Biomedical applictions of trastuzumab: as a therapeutic agent and a targeting ligand. Medicinal Research Reviews35 (4), 849-876. (IF=12.944)
  43. I Singh, R Swami, D Pooja, MK Jeengar, W Khan, R Sistla (2015). Lactoferrinbioconjugated solid lipid nanoparticles: a new drug delivery system for potential brain targeting.  Journal of Drug Targeting 1-12. (IF=5.121)
  44. D Pooja, S Panyaram, H Kulhari, RS Sunder, R Sistla (2014). Xanthan gum stabilized gold nanoparticles: characterization, biocompatibility, stability and cytotoxicity. Carbohydrate Polymers 110:1-9. (IF=9.381)
  45. D Pooja, H Kulhari, MK Singh, S Mukherjee, R Sistla (2014). Dendrimer-TPGS Mixed Micelles for Enhanced Solubility and Cellular Toxicity of Taxanes. Colloids and Surfaces B: Biointerfaces 121:461-468. (IF=5.268)
  46. D Pooja, DJB Bikkina, H Kulhari, N Nikhila, S Chinde, AK Tiwari. (2014) Fabrication, Characterization and Bioevaluation of Silibinin Loaded Chitosan Nanoparticles. International Journal of Biological Macromolecules69: 267-73. (IF=6.953)
  47. HKulhari, D Pooja, S. Srivastava, VGM Naidu, R Sistla. (2014)Peptide conjugated polymeric nanoparticles as a carrier for targeted delivery of docetaxel. Colloids and Surfaces B: Biointerfaces117, 166–173. (IF=5.268).
  48. H Kulhari, D Pooja, MK Singh, R Sistla. (2014) Colloidal stability and physicochemical characterization of bombesin conjugated biodegradable nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects443, 459-466. (IF=4.539)
  49. H Kulhari, D Pooja, MK Singh, AS Chauhan (2015). Optimization of carboxylate-terminated poly (amidoamine) dendrimer-mediated cisplatin formulation. Drug Development and Industrial Pharmacy 41 (2), 232-238. (IF:3.225)
  50. H Kulhari, D Pooja*, SK Prajapati, AS Chauhan (2013). Pharmacokinetic and pharmacodynamic studies of poly (amidoamine) dendrimer-based simvastatin oral formulations for the treatment of hypercholesterolemia. Molecular Pharmaceutics 10 (7), 2528-2533. (IF: 4.939)
  51. G Swami, D Pooja, H Kulhari, KM Kymonil, SA Saraf (2011). Surface modification of poly (l-lactic acid) microspheres for site-specific delivery of ketoprofen for chronic inflammatory disease. Journal of Drug Targeting 21 (3), 232-239. (IF: 5.121)
  52. H Kulhari, D Pooja, H Narayan, L Meena, SK Prajapati (2011). Design and evaluation of ocusert for controlled delivery of flurbiprofen sodium. Current Eye Research 36 (5), 436-441. (IF: 2.424)
  53. H Kulhari, D Pooja, SK Prajapati, AS Chauhan (2011). Performance evaluation of PAMAM dendrimer-based simvastatin formulations. International Journal of Pharmaceutics 405 (1), 203-209. (IF: 5.875).

Awards / Honours / Achievements / Appreciation

  • Endeavour Research Fellowship awarded by Department of Education, Australian Government (July 2015-Dec 2015).
  • Senior Research Fellowship by Council of Scientific and Industrial Research, New Delhi. (May 2012-May 2016)
  • Junior Research Fellowship awarded by All India Council for Technical Education, New Delhi. (2006-2008)
  • Qualified Graduate Aptitude Test in Engineering (GATE) 2008 with GATE Score 527 (Percentile 99.12), organized by Indian Institute of Science, Bangalore.
  • Best Research Paper Award in International Conference on Nanoscience and Nanotechnology - "NanoSciTech-2017” held at Panjab University, Chandigarh on 9-10th November 2017.
  • Best poster award in KEPLER-2007, held at J.C. Bose institute of life sciences, Bundelkhand University, Jhansi.
  • Selected for Fee Waiver Scheme for graduation by State Government of Rajasthan, Jaipur in 2001.
  • Gargi Award by State Government of Rajasthan, Jaipur in 1997.

National/International Presentations

  1. First International online conference on blends, composites, Bio-composites and Nanocomposites. ICNC 2020 held at Mahatma Gandhi University, Kottayam, Kerala, India on 9-11th October 2020.
  2. International E-conference on Recent Trends in Drug Discovery, Diagnostics and Therapeutics held at VIGNAN’s Foundation for Science, Technology & Research, Guntur on 2-4thJuly 2020.
  3. National Conference on Applied Material Science held at      Central University of Gujarat, Gandhinagar on 6-7th April 2018.
  4. International Conference on Nanoscience and Nanotechnology - "NanoSciTech-2017” held at Panjab University, Chandigarhon9-10th November 2017.
  5. AICTE sponsored National Seminar on-Recent Advances in Pharmaceutical Education and Research, held at BNIPS, Udaipur on 5-6th March 2014.
  6. International Conference on Chemical Biology Disease Mechanisms and Therapeutics (ICCB-2014) held at CSIR-IICT, Hyderabad on 6-8th Feb., 2014.
  7. 27th International Carbohydrate Symposium, held at Indian Institute of Science, Bangalore on 12-17th January 2014.
  8. AICTE sponsored National seminar on Recent trends in development of novel drug delivery systems held at Jaipur College of Pharmacy, Jaipur on 16-17th March 2013
  9. AICTE sponsored national seminar on Quality perspectives of Herbal Cosmetics held in Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur on 8-9th September 2007.